Recessive alleles are usually loss-of-function mutations.

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Recessive alleles are typically masked by dominant alleles and do not produce a functional protein or produce a non-functional version of the protein. This type of mutation is known as a loss-of-function mutation. However, there are rare cases where recessive alleles produce a gain-of-function mutation, where the protein produced by the mutated allele has an abnormal or overactive function.

Recessive Alleles Are Usually Loss-Of-Function Mutations