Is it possible to correct for the effects of multiple crossovers in calculating map distances by applying a linear mapping function.

Question

Quizplus · Accepted Answer

Linear mapping functions are used to calculate genetic distances between loci assuming a linear relationship between recombination frequency and physical distance. They cannot correct for the effects of multiple crossovers, which can complicate the calculation of map distances. Other methods, such as maximum likelihood or regression modeling, are typically used to account for multiple crossovers.

Is It Possible to Correct for the Effects of Multiple