Small DNA tumor viruses such as SV40 and HPV have viral oncogenes that are not homologs of host cell genes.Some of these novel viral oncogenes make proteins that exert their tumorigenic effect by
A) binding to and inactivating pRB.
B) making Gag,Pol and Env proteins more active.
C) causing cellular proto-oncogenes to mutate into oncogenes.
D) causing apoptosis in target tissues.
E) inactivating the immune system.
Correct Answer:
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Q13: v-onc genes are found in
A)vital cells.
B)viral cells.
C)cancer-causing
Q14: Cell proliferation in culture is normally limited
Q15: Mutations in a normal growth-stimulating gene are
Q16: Cancer may arise as a result of
A)mutations
Q17: In retroviruses,the pol gene product is a(n)
A)DNA
Q19: Agents that can induce cancer through mutagenesis
Q20: Reverse transcriptase,the enzyme responsible for copying viral
Q21: Describe Knudson's two-mutation model: When and where
Q22: Programmed cell death,or apoptosis,is a necessary and
Q23: List the ways in which proto-oncogenes may
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