Inherited mutant tumor suppressors produce a dominant susceptibility to cancer,but the mutant alleles are actually recessive in the cancer.

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Inherited mutant tumor suppressors, such as BRCA1 and BRCA2, produce a dominant susceptibility to cancer, which means that individuals with just one mutation in the tumor suppressor gene have an increased risk of developing cancer. However, in order for the cancer to actually develop, both copies of the gene (one from each parent) must be mutated, making the mutant alleles recessive in the cancer itself.

Inherited Mutant Tumor Suppressors Produce a Dominant Susceptibility to Cancer,but