Li-Fraumeni syndrome is a rare inherited disease that greatly increases a person's risk of developing several types of cancer.This disease stems from a mutation in the TP53 tumor suppressor gene (Nichols et al.2001.Cancer Epidemiol Biomarkers Prev 10:83-87).In most cases,approximately 95% of the mutations can be detected by sequence analysis of exons 4 through 9.If you isolated and analyzed DNA from a Li-Fraumeni patient,what genotype should you find in DNA isolated from
a.normal tissue?
b.malignant tissue?

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The Answer of Li-Fraumeni syndrome is a rare inherited disease that greatly increases a person's risk of developing several types of cancer.This disease stems from a mutation in the TP53 tumor suppressor gene (Nichols et al.2001.Cancer Epidemiol Biomarkers Prev 10:83-87).In most cases,approximately 95% of the mutations can be detected by sequence analysis of exons 4 through 9.If you isolated and analyzed DNA from a Li-Fraumeni patient,what genotype should you find in DNA isolated from
a.normal tissue?
b.malignant tissue?

Li-Fraumeni Syndrome Is a Rare Inherited Disease That Greatly Increases