Where does cleavage of the scissile bond by chymotrypsin occur?
A) between a His and Ser amino acid
B) on the N-terminal side of a Phe or Trp residue
C) on the C-terminal side of a Phe or Trp residue
D) at the N-terminal amino acid
E) on the C-terminal side of an Arg or Lys amino acid

Question

Quizplus · Accepted Answer

Chymotrypsin cleaves peptide bonds on the C-terminal side of aromatic amino acids such as phenylalanine (Phe) or tryptophan (Trp), not on the N-terminal side or specifically between His and Ser amino acids, or at the N-terminal amino acid, or on the C-terminal side of Arg or Lys.

Where Does Cleavage of the Scissile Bond by Chymotrypsin Occur