Which amino acid side chain in thymidylate synthase activates the ring of dUMP, making C-5 a good nucleophile?
A) cysteine
B) aspartate
C) glutamine
D) tyrosine
E) serine
Correct Answer:
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Q29: The displacing nucleophile in pyrimidine synthesis is
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Q31: Which enzyme(s), in nucleotide biosynthesis pathways, use(s)
Q32: In the de novo synthesis of DNA
Q33: What is an ATP-grasp fold?
Q35: In addition to UTP, the synthesis of
Q36: Why is nucleotide synthesis an important pathway
Q37: TMP is made from
A) dTMP.
B) UTP.
C) CTP.
D)
Q38: Briefly describe, in one or two sentences,
Q39: What enzyme carries out this reaction?
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