Which of the following properties affects the effective concentration of a drug at the target site?
A) the rate of absorption of the drug
B) the extent of distribution or compartmentalization of the drug
C) the efficiency of metabolism of the drug
D) the ease of excretion of the drug and/or its metabolites
E) All of the answers are correct.

Question

Quizplus · Accepted Answer

All of the listed properties affect the effective concentration of a drug at the target site. The rate of absorption influences how quickly a drug enters systemic circulation, the extent of distribution determines how widely and where within the body a drug is dispersed, the efficiency of metabolism can alter a drug's activity and duration of effect, and the ease of excretion impacts how long a drug and its metabolites remain in the body.

Which of the Following Properties Affects the Effective Concentration of a Drug