Monoamine NTs are degraded by
A)acetylcholinesterase.
B)monoamine oxidase.
C)catechol-O-methyltransferase.
D)adenylate cyclase.

Question

Quizplus · Accepted Answer

Monoamine NTs such as dopamine, serotonin, and norepinephrine are degraded by the enzyme monoamine oxidase (MAO). This process helps regulate the concentration of these NTs in the synapse and prevents overstimulation of postsynaptic receptors. Acetylcholinesterase is responsible for degrading the NT acetylcholine, not monoamines. Catechol-O-methyltransferase (COMT) primarily degrades dopamine, but is not the primary enzyme responsible for the degradation of monoamine NTs. Adenylate cyclase is an enzyme involved in intracellular signaling and does not directly degrade NTs.

Monoamine NTs Are Degraded by