___________________ comprise an important family of enzymes that can break down extracellular matrix proteins but require a zinc ion cofactor.
A)Matrix metallohydrolases
B)Matrix phosphokinases
C)Matrix metalloproteinases
D)None of these choices are correct.

Question

Quizplus · Accepted Answer

Matrix metalloproteinases (MMPs) are a family of enzymes that can break down extracellular matrix proteins but require a zinc ion cofactor for their enzymatic activity. They play important roles in tissue remodeling, wound healing, and development, as well as in pathological conditions such as cancer, arthritis, and cardiovascular diseases. MMPs are involved in the degradation of various extracellular matrix components, including collagen, elastin, gelatin, fibronectin, laminin, and proteoglycans. They are regulated by various mechanisms, including transcriptional control, post-transcriptional modifications, activation of pro-enzymes, and inhibition by endogenous inhibitors (tissue inhibitors of metalloproteinases or TIMPs).

___________________ Comprise an Important Family of Enzymes That Can Break