A defect in the enzyme that catalyzes the formation of melanin from DOPA results in

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Albinism is a genetic disorder characterized by the absence or reduction of melanin pigment in the skin, hair, and eyes. Melanin is produced from the amino acid tyrosine by a series of enzymatic reactions that involve the enzyme tyrosinase. A defect in this enzyme results in the inability to produce melanin and leads to the symptoms of albinism. DOPA is an intermediate compound in the pathway of melanin synthesis that is converted to melanin by tyrosinase. Thus, a defect in this enzyme would also affect the formation of melanin from DOPA. Phenylketonuria, lactose intolerance, and maple-syrup disease are not related to melanin synthesis.

A Defect in the Enzyme That Catalyzes the Formation of Melanin