Blocking the CD8 coreceptor would cause
A)decreased activation of macrophages.
B)decreased activation of helper T lymphocytes.
C)decreased activation of cytotoxic T cells.
D)decreased activation of the target cells.

Question

Quizplus · Accepted Answer

CD8 is a coreceptor that is expressed on the surface of cytotoxic T cells. It interacts with MHC class I molecules on target cells, enhancing the cytotoxic activity of T cells. Blocking the CD8 coreceptor would therefore result in decreased activation of cytotoxic T cells, as they would not be able to effectively recognize and eliminate target cells. Blocking CD8 would not affect the activation of macrophages or helper T lymphocytes directly, nor would it affect the target cells themselves.

Blocking the CD8 Coreceptor Would Cause