The primarily hydrophilic leader sequence of secretory proteins allows it to be inserted into the cisterna of the endoplasmic reticulum.

Name: The primarily hydrophilic leader sequence of secretory proteins allows it to be inserted into the cisterna of the endoplasmic reticulum.
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The leader sequence of secretory proteins is primarily hydrophobic, not hydrophilic, which allows it to interact with the hydrophobic core of the endoplasmic reticulum membrane and facilitate insertion into the ER.

The Primarily Hydrophilic Leader Sequence of Secretory Proteins Allows It