Atrophy of the pancreatic acinar cells occurs in response to
A)increased gastrin secretion.
B)decreased sympathetic stimulation.
C)decreased cholecystokinin secretion.
D)increased secretin secretion.

Question

Quizplus · Accepted Answer

Atrophy of the pancreatic acinar cells occurs in response to decreased cholecystokinin secretion. Cholecystokinin (CCK) is a hormone released by the small intestine in response to the presence of fat and protein in the duodenum. It stimulates the pancreas to release digestive enzymes, including lipase, amylase, and proteases. Without CCK, the pancreatic acinar cells do not receive the signal to release enzymes, leading to atrophy. Increased gastrin or secretin secretion would not directly affect pancreatic acinar cells, and decreased sympathetic stimulation is not associated with pancreatic atrophy.

Atrophy of the Pancreatic Acinar Cells Occurs in Response to