The renal plasma clearance of a substance that is filtered and reabsorbed must be less than the GFR.

Question

Quizplus · Accepted Answer

If a substance is reabsorbed by the tubules, it will not be excreted into the urine and its renal plasma clearance will be lower than the GFR. This is because the clearance only includes the amount of the substance that is completely cleared from the plasma and excreted in the urine. If some of the substance is reabsorbed, it will not be completely cleared from the plasma and its clearance will be lower than the GFR.

The Renal Plasma Clearance of a Substance That Is Filtered