The osmotic diuretic mannitol inhibits salt and water absorption in the proximal convoluted tubule.

Question

Quizplus · Accepted Answer

Mannitol is not a specific inhibitor of salt and water absorption in the proximal convoluted tubule, but rather a non-absorbable solute that increases the osmolarity of the filtrate, promoting water diuresis and decreasing renal blood flow. Its effect is more pronounced in the thin descending limb of the loop of Henle and the collecting duct, where water reabsorption is obligatorily driven by the osmotic gradient.

The Osmotic Diuretic Mannitol Inhibits Salt and Water Absorption in the Proximal