The chloride shift and its reverse play an important role in the acid-base balance of the blood.

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The chloride shift refers to the movement of chloride ions out of red blood cells and into plasma as bicarbonate ions move in the opposite direction. This helps to maintain the balance of ions and pH in the blood. The reverse occurs in the lungs during gas exchange. Therefore, the chloride shift and its reverse play a crucial role in the acid-base balance of the blood.

The Chloride Shift and Its Reverse Play an Important Role