Nicotinic agonists would bind cholinergic receptors on preganglionic autonomic neurons.

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Nicotinic agonists are molecules that bind to and activate nicotinic acetylcholine receptors (nAChRs). These receptors are found on both autonomic ganglia and skeletal muscle cells. When nicotinic agonists bind to nAChRs on preganglionic autonomic neurons in the ganglia, they cause depolarization of the membrane and the subsequent release of neurotransmitters to postganglionic neurons.

Nicotinic Agonists Would Bind Cholinergic Receptors on Preganglionic Autonomic Neurons