In the Na+/K+ pump,three sodium ions from inside the cell must enter the carrier first.

Question

Quizplus · Accepted Answer

The Na+/K+ pump transports three sodium ions from the extracellular fluid into the cell and two potassium ions out of the cell, against their respective concentration gradients. Three sodium ions bind to the carrier protein first, causing a conformational change that allows the pump to release the sodium ions into the cytoplasm and bind two potassium ions from the cytoplasm. The pump then undergoes another conformational change to release the potassium ions back into the extracellular fluid and restore the original conformation of the carrier protein.

In the Na+/K+ Pump,three Sodium Ions from Inside the Cell