Pavlov found that forcing an organism to continue to solve an increasingly difficult discrimination problem often resulted in:

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Pavlov's experimentation with increasingly difficult discrimination tasks often resulted in experimental neurosis, which is a state of extreme emotional disturbance in which an organism is caught between two conflicting stimuli. This can result in erratic, neurotic behavior and can be a significant impediment to learning.

Pavlov Found That Forcing an Organism to Continue to Solve