Would ID 50 and LD 50 necessarily be the same for a given virus? Why or why not?

ID 50 and LD 50 are measures of the infectivity and lethality, respectively, of a virus. These values are not necessarily correlated, meaning a virus can be highly infectious but only marginally lethal, as in the case of the rhinovirus. Thus, the values for ID 50 and LD 50 may be different for a given virus.

Would ID 50 and LD 50 necessarily be the same for a given virus? Why or why not?

ID 50 and LD 50 are measures of the infectivity and lethality, respectively, of a virus. These values are not necessarily correlated, meaning a virus can be highly infectious but only marginally lethal, as in the case of the rhinovirus. Thus, the values for ID 50 and LD 50 may be different for a given virus.

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Would ID₅₀ and LD₅₀ Necessarily Be the Same for a Given

Question 122

Multiple Choice

Would ID₅₀ and LD₅₀ necessarily be the same for a given virus? Why or why not?

A) Yes, because the number of viruses that infect 50% of a test population should also kill 50% of that test population.
B) No, because a virus may be highly infectious (very low ID₅₀ value) but only marginally lethal (very high LD₅₀ value) . A prime example of this is the rhinovirus (common cold virus) .
C) No, because very few viruses are lethal, yet many are highly infectious. The 2 values should ALWAYS be different.
D) Yes, because what we're actually describing here is infection/killing of individual CELLS, not of entire organisms. If a cell is infected, it will always be killed.

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