The Enzyme-Substrate Complex Is

The enzyme-substrate complex is

A) not strong and will freely dissociate after it stresses certain chemical bonds in a substrate.
B) secured by covalent bonds to one or more points in the active site of the enzyme.
C) able to display unique spectroscopic characteristics not seen by either the enzyme or the substrate alone.
D) proved by the saturation effect in which the reaction rate reaches a maximum even through more substrate is added.
E) all of the choices are correct.