A base substitution will lead to a frame-shift mutation.

Question

Quizplus · Accepted Answer

A base substitution involves the replacement of one base with another, but it does not necessarily result in a frame-shift mutation. A frame-shift mutation occurs when one or more nucleotides are inserted or deleted from the DNA sequence, causing a shift in the reading frame of the genetic code. This can occur due to an insertion or deletion mutation, but not necessarily a base substitution.

A Base Substitution Will Lead to a Frame-Shift Mutation