Oxytocin stimulates myometrial contractions most strongly when plasma progesterone levels are low relative to estrogen.

Question

Quizplus · Accepted Answer

Oxytocin is most effective in stimulating the contraction of the uterus when the levels of progesterone, which inhibits oxytocin's effects, are low relative to the levels of estrogen. This is because estrogen stimulates the production of oxytocin receptors on the myometrial cells, making them more responsive to oxytocin stimulation. When progesterone levels drop, the inhibitory effect is removed, allowing oxytocin to stimulate strong contractions.

Oxytocin Stimulates Myometrial Contractions Most Strongly When Plasma Progesterone Levels