Renin is secreted by juxtaglomerular cells in the renal afferent arterioles. Its secretion is actually stimulated by low levels of Na+ in the macula densa and low blood pressure, not high levels or elevated blood pressure. Renin acts on angiotensinogen to form angiotensin I, which is then converted to angiotensin II, stimulating aldosterone secretion indirectly.

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Renin

Question 29

Multiple Choice

Renin

A) Is secreted by juxtaglomerular cells in renal afferent arterioles
B) Secretion is enhanced by high levels of Na⁺ in the macula densa
C) Secretion is stimulated by elevated blood pressure in the renal afferent arterioles
D) Acts on the adrenal cortex to stimulate aldosterone secretion
E) Is described by all of these things

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