Which of the following drugs would not enhance the activity of serotoninergic neurons?
A)A drug that increases the uptake of tryptophan into neurons
B)A drug that inhibits enzymes that break down serotonin
C)A drug that facilitates reuptake of serotonin by serotoninergic neurons
D)A drug that up-regulates serotonin receptors

Question

Quizplus · Accepted Answer

Facilitating reuptake of serotonin by serotoninergic neurons would decrease the amount of serotonin available in the synaptic cleft and would not enhance the activity of serotoninergic neurons.

Choice A would enhance the activity of serotoninergic neurons by increasing the availability of tryptophan, the precursor to serotonin.
Choice B would enhance the activity of serotoninergic neurons by inhibiting the breakdown of serotonin, leading to increased levels in the synaptic cleft.
Choice D would enhance the activity of serotoninergic neurons by increasing the number of available serotonin receptors for serotonin molecules to bind to.

Which of the Following Drugs Would Not Enhance the Activity