During a high-frequency burst of action potentials down an axon,the amount of neurotransmitter released with each action potential increases (for a finite time).

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This phenomenon is known as synaptic facilitation and occurs as a result of residual calcium ion buildup in the presynaptic terminal during successive action potentials. This leads to a greater release of neurotransmitter with each subsequent action potential for a finite period of time.

During a High-Frequency Burst of Action Potentials Down an Axon,the