Kevin was a participant in a clinical study to determine how much niacin cures pellagra,the niacin deficiency disease.During the study,he consumed only a formula diet that was deficient in niacin.After developing pellagra,he was given 2 mg of niacin a day for 2 weeks,but he still suffered from the disease,so the scientists added 2 mg of the vitamin to Kevin's formula.By the beginning of the 5th week of the study,the researchers noticed that Kevin's signs and symptoms were greatly improved.At the end of the 5th week,he was feeling fine.The researchers concluded that

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The researchers concluded that Kevin's niacin requirement was about 4 mg a day based on the fact that his symptoms improved with a daily intake of 4 mg (2 mg supplement plus 2 mg added to his formula) after not responding to a 2 mg supplement alone. However, this study is specific to Kevin's individual needs and cannot be generalized to establish an RDA or AI for niacin for the general population.

Kevin Was a Participant in a Clinical Study to Determine