Which Is Incorrect About Enzymes

Which is incorrect about enzymes?

A) Enzyme repressors disrupt enzyme active site shape.
B) A noncompetitive inhibitor of enzymes interferes with the active site of the enzyme.
C) Enzymes need to have a precise shape to work correctly.
D) In humans,extremely high fevers can be fatal because enzymes begin to unfold and stop working.
E) Some enzymes can work in extreme temperatures or very low pH.