The first mutation typically detected in FAP (familial adenomatous polyposis)colon cancer is

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Quizplus · Accepted Answer

The first and most common mutation detected in FAP is in the APC (adenomatous polyposis coli) gene, which is a tumor suppressor gene. This mutation leads to the formation of multiple adenomatous polyps in the colon, which can progress to cancer if not removed. TGF (transforming growth factor), p53, and PRL-3 mutations have been associated with other types of cancer but are not typically detected as the first mutation in FAP.

The First Mutation Typically Detected in FAP (Familial Adenomatous Polyposis)colon