Matthew has the inherited form of the eye cancer retinoblastoma (RB).His disease is caused by

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Inherited forms of RB are caused by a germinal mutation in one RB allele, which is present in all cells of the individual's body, and a somatic mutation in the other allele, which occurs later in development in one or more cells of the retina. This leads to the loss of both functional copies of the RB gene in those cells, allowing them to divide uncontrollably and form tumors.

Matthew Has the Inherited Form of the Eye Cancer Retinoblastoma