A person who is a heterozygote for G6PD deficiency is protected against

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Heterozygotes for G6PD deficiency have protection against the malaria parasite because G6PD plays a role in protecting red blood cells from damage caused by oxidative stress, a process that is needed for the malaria parasite to survive within the red blood cell. Thus, individuals with G6PD deficiency are resistant to malaria because their red blood cells have a reduced ability to generate reactive oxygen species, which are toxic to the parasite.

A Person Who Is a Heterozygote for G6PD Deficiency Is