In a form of early-onset Alzheimer disease caused by a mutation on chromosome 14,A is changed to T at the first position of codon 146,which substitutes leucine for methionine.This mutation is a _____ and is _____.
A)transversion;nonsense
B)transversion;missense
C)transition;missense
D)transition;nonsense

Question

Quizplus · Accepted Answer

The substitution of A to T is a transversion and the resulting change in the codon leads to a change in the amino acid, which is a missense mutation.

In a Form of Early-Onset Alzheimer Disease Caused by a Mutation