A likely biological basis of major depressive disorder is
A)reuptake pumps for serotonin in the presynaptic neuron membrane that do not function adequately.
B)absent reuptake pumps for serotonin in the presynaptic neuron membrane.
C)reuptake pumps for serotonin in the postsynaptic neuron membrane that do not function adequately.
D)reuptake pumps for serotonin in the postsynaptic neuron membrane that are overactive,depleting serotonin in the synapse.

Question

Quizplus · Accepted Answer

Research has shown that major depressive disorder is associated with a decrease in serotonin transmission, and one possible biological basis for this is that the reuptake pumps for serotonin in the presynaptic neuron membrane do not function adequately, leading to a decrease in serotonin levels in the synapse. This is the basis for the use of selective serotonin reuptake inhibitors (SSRIs) as a treatment for depression, as they prevent the reuptake of serotonin and increase its availability in the synapse.

A Likely Biological Basis of Major Depressive Disorder Is