A boy developed signs of sexual maturity at age 3.A possible diagnosis is

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Congenital adrenal hyperplasia due to 21-hydroxylase deficiency can cause early onset of puberty due to increased production of adrenal androgens. This can result in signs of sexual maturity appearing in boys as early as age 3. XY female syndrome and XX male syndrome involve abnormalities in sex chromosome makeup and would not typically present with signs of sexual maturity at such a young age. Pseudohermaphroditism due to 5-alpha reductase deficiency may cause ambiguous genitalia at birth, but is unlikely to manifest as sexual maturation at such an early age.

A Boy Developed Signs of Sexual Maturity at Age 3