One line of evidence that humans arose in Africa is the observation that:

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The fact that Africans have the most diverse mitochondrial DNA sequences is evidence that humans likely originated in Africa. Mitochondrial DNA is passed down maternally, so by comparing the mitochondrial DNA sequences of different populations, researchers can estimate how long ago populations diverged from one another. The high diversity of mitochondrial DNA sequences in African populations suggests that they have been evolving for a longer period of time than populations outside of Africa, consistent with the idea that humans emerged from Africa before spreading to other parts of the world.

One Line of Evidence That Humans Arose in Africa Is