Why did the researchers induce cancer in mice by injecting cancer cells,instead of just doing the experiment on isolated cancer cells in culture?

Question

Quizplus · Accepted Answer

Angiogenesis, the formation of blood vessels, occurs in a whole organism, and this process is essential for the growth and spread of cancer in the body. Injecting cancer cells into the mice allowed the researchers to observe the complex interactions between the cancer cells and the surrounding tissue, including the activation of angiogenesis. This would not have been possible if the experiment had been conducted on isolated cancer cells in culture.

Why Did the Researchers Induce Cancer in Mice by Injecting