The first single-gene disorder for which the mechanism of mutation was understood was
A) cystic fibrosis.
B) Duchenne muscular dystrophy.
C) hemophilia.
D) sickle cell disease.
E) diabetes mellitus.

Question

Quizplus · Accepted Answer

The mechanism of mutation causing sickle cell disease was first understood in 1949, making it the first single-gene disorder for which the mechanism was elucidated.

The First Single-Gene Disorder for Which the Mechanism of Mutation