Mutations are more likely to occur in or near repeated DNA sequences because
A) these bases are unstable.
B) bases in the strand can form base pairs, generating loops that interfere with replication and repair enzymes.
C) the repeats hold onto the replication enzymes, causing base mismatches.
D) the repeats attract and bind to mutagens, increasing the mutation rate.
E) repeated sequences do not have a sugar-phosphate backbone.

Question

Quizplus · Accepted Answer

Repeated DNA sequences can form secondary structures, such as hairpin loops, which can interfere with DNA replication and repair enzymes. This can lead to mistakes in replication, such as insertions or deletions, resulting in mutations. Additionally, some repeated sequences have a high mutation rate due to slippage during replication, where the repeat sequences misalign and cause base mismatches.

Mutations Are More Likely to Occur in or near Repeated