A mutation that changes one particular amino acid into another can affect the functioning of other amino acids farther away in the primary sequence due to

Question

Quizplus · Accepted Answer

Amino acids in a protein sequence are held together by chemical bonds, and the sequence determines the ultimate three-dimensional shape of the protein. A change in one amino acid can alter the way the protein folds, which can in turn affect the functioning of other amino acids farther away in the sequence. This is a common way that mutations can have significant effects on protein structure and function.

A Mutation That Changes One Particular Amino Acid into Another