A major distinction of genome-wide association studies,compared to the more traditional approaches of empiric risk,heritability,adoptee and twin studies,is that
A) GWA studies pepper the entire genome with markers, so that even genes that would not be expected to contribute to a phenotype can be discovered.
B) GWA studies actually sequence entire genomes.
C) GWA studies can be performed on healthy individuals.
D) GWA studies consider already-known traits.
E) GWA studies are conducted on RNA sequences.

Question

Quizplus · Accepted Answer

Genome-wide association studies (GWA studies) use a large number of markers that are distributed across the entire genome in order to identify genetic variants that are associated with a particular trait or disease. In contrast to traditional approaches such as empiric risk or twin studies, GWA studies are not limited to specific candidate genes or regions of the genome. This allows for the identification of unexpected genes or variants that may contribute to the phenotype in question.

A Major Distinction of Genome-Wide Association Studies,compared to the More