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Current Thinking About the Cause of Hutchinson-Gilford Syndrome,which Is a Severe

Question 65

Multiple Choice

Current thinking about the cause of Hutchinson-Gilford syndrome,which is a severe segmental progeroid syndrome,is that


A) the cellular clock ticks much too fast.
B) the part of the brain that controls aging is damaged.
C) abnormal lamin A protein stresses the nuclear membrane, disturbing DNA repair such that mutations accumulate that cause the diseases of aging.
D) a protein called progerin forms clumps in the brain in a way that removes DNA from the tips of telomeres, shortening chromosomes and lifespan.
E) starvation in the uterus sets the stage for diseases of the aged occurring in childhood.

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