In the section "Investigating Life: Cutting Off a Tumor's Supply Lines in the War on Cancer",the standard chemotherapy drug forms crosslinks between the two strands of DNA in a chromosome.How is this effective in chemotherapy?

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Standard chemotherapy drugs that form crosslinks between the two DNA strands in a chromosome are effective because they delay DNA replication. This delay can lead to cell death, as cells rely on proper DNA replication in order to divide and function properly. By disrupting this process, the chemotherapy drugs can target rapidly dividing cancer cells and prevent them from spreading.

In the Section "Investigating Life: Cutting Off a Tumor's Supply