When an end product of a reaction is in excess and inhibits the first enzyme of the pathway,this is an example of negative feedback.

Question

Quizplus · Accepted Answer

In negative feedback, the end product of a reaction inhibits the activity of an earlier enzyme in the pathway, ultimately slowing down the overall rate of the pathway. This scenario is described in the statement, where the excess end product inhibits the first enzyme in the pathway.

When an End Product of a Reaction Is in Excess