Animal self-administration experiments and studies of drug choice among humans indicate that
A)benzodiazepines have no dependence liability.
B)rats and people are very different in the drugs they choose to self-administer.
C)short-acting barbiturates are more likely to lead to dependence than any of the benzodiazepines.
D)all of the benzodiazepines have high dependence liability.

Question

Quizplus · Accepted Answer

Short-acting barbiturates are more likely to lead to dependence than any of the benzodiazepines, as indicated by both animal self-administration experiments and studies of drug choice among humans. This is because the rapid onset and short duration of action of short-acting barbiturates can lead to a higher potential for abuse and dependence compared to benzodiazepines, which generally have a longer duration of action and a slower onset.

Animal Self-Administration Experiments and Studies of Drug Choice Among Humans