To receive diagnosis of substance dependence an individual must satisfy at least 3 diagnostic criteria,one which has to be a symptom of physical dependence (tolerance or withdrawal).

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The DSM-IV required at least 3 criteria for substance dependence, but not necessarily including tolerance or withdrawal. The DSM-5 has replaced "substance dependence" with "substance use disorder" and does not require physical dependence symptoms.

To Receive Diagnosis of Substance Dependence an Individual Must Satisfy