Which of the Following Statements Are True of O₂ and CO₂

Which of the following statements are true of O₂ and CO₂ transport in the blood? (Read carefully and select all of the correct statements.)

A) Most CO₂ is carried in the blood as bicarbonate ions.
B) Most oxygen is carried by the iron in blood plasma.
C) As the pH of tissues decreases,more oxygen is released from hemoglobin.
D) Increased CO₂ in the blood makes the blood pH more alkaline.
E) As the temperature of tissues increases,less oxygen is released from hemoglobin.
F) Too much CO₂ in the blood results in hypoxia.