The purpose of the invariant chain is to block the peptide-binding site of:

Question

Quizplus · Accepted Answer

The invariant chain, also known as CD74, is a chaperone molecule that blocks the peptide-binding site of nascent class II MHC molecules in order to prevent premature antigen presentation. This allows the MHC molecules to traffic to the endosome and acquire antigenic peptides for later presentation to CD4+ T cells. The invariant chain does not interact with antibody molecules or class I MHC molecules, and has no effect on T-cell receptors.

The Purpose of the Invariant Chain Is to Block the Peptide-Binding