A critical receptor involved in the second signal for T-dependent B-cell activation is:

Question

Quizplus · Accepted Answer

The critical receptor involved in the second signal for T-dependent B-cell activation is CD40. This receptor, expressed on the surface of B cells, is stimulated by CD40 ligand (CD40L) expressed on activated T cells. This interaction leads to the upregulation of co-stimulatory molecules and the production of cytokines, resulting in B-cell proliferation, differentiation, and antibody secretion. CD3 is a complex of proteins involved in T-cell receptor signaling. CD19 is a B-cell co-receptor, and surface IgM is part of the B-cell receptor complex. While these molecules may also be involved in B-cell activation, they do not play the critical role of CD40 in the second signal of T-dependent activation.

A Critical Receptor Involved in the Second Signal for T-Dependent