The region of an antibody molecule that exhibits the greatest variability from antibody to antibody is known as the:

Question

Quizplus · Accepted Answer

The hypervariable or complementary determining region (CDR) of an antibody is the part of the molecule that differs the most from one antibody to another. It is responsible for binding to specific antigenic determinants on pathogens or other foreign substances. In contrast, the constant region (C region) of an antibody remains relatively unchanged and determines the functional properties of the antibody such as its ability to activate complement, bind to Fc receptors, and cross the placenta. The Fc region of an antibody refers to the fragment crystallizable region, which is located at the bottom of the Y-shaped antibody molecule and plays a role in recruiting other immune cells to mount an immune response.

The Region of an Antibody Molecule That Exhibits the Greatest